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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human ovarian cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PDGFA
Abbre PDGFA
Synonyms PDGF A,  PDGF A chain,  PDGF subunit A,  PDGF-1,  PDGF1,  PDGFA,  Pla,  Platelet derived growth factor alpha chain,  Platelet derived growth factor alpha isoform 2 preproprotein,  Platelet derived growth factor alpha polypeptide,  Platelet-derived growth factor A chain
Swissprot
Cellular Localization Secreted.
Concentration 1.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Immunology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Other Clones

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Unconjugated

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