PE Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] (E-AB-F1016UD)
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For research use only.
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | PE Mouse IgG1, κ Isotype Control[MOPC-21] |
| Abbre | CD47 |
| Synonyms | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Clone No. | MIAP410 |
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |
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