Name: PE Anti-Mouse CD146 Antibody[ME-9F1]
Brand: Elabscience
SKU: E-AB-F1395D
Price: 53.0 USD
Availability: InStock

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD146
Synonyms	S-Endo 1 antigen, MUC18, MCAM, Mel-CAM, A32 antigen
Swissprot	P10810
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	ME-9F1
Conjugation	PE
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD146, also known as melanoma cell adhesion molecule (MCAM or Mel-CAM), MUC18, S-Endo1, and A32 antigen, is an integral membrane glycoprotein that belongs to the Ig superfamily. CD146 is strongly expressed by murine vascular endothelial cells. It is expressed on about 30% of neutrophils and 60% of NK cells. Unlike in humans, CD146 is undetectable on monocytes, dendritic cells, T cells, NKT cells, B cells, or smooth muscle cells in mouse. It has been reported that an increase in CD146 expression is associated with NK cell maturation. Combined with using CD27 and CD11b staining, CD146 may be an alternative marker to detect final stages of NK cell maturation and define NK cell subsets. CD146+ NK cells were found to be less cytotoxic and to produce less IFNγ than CD146- NK cells upon stimulation with target cells or activating antibodies. The role of CD146 on NK cell migration has yet to be investigated. The identification of CD146 ligand(s) will be crucial to address this issue.

Cat.No.	Product Name	Sizes
E-CK-A105	10×ACK Lysis Buffer	500mL , 200mL , 100mL
E-CK-A107	Cell Staining Buffer	500mL , 200mL , 100mL

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All

AA98

ME-9F1

P1H12

Size	Price	Qty
100Tests	$ 95.00	- +
50Tests	$ 53.00	- +
100Tests×2	$ 171.00	- +

PE Anti-Mouse CD146 Antibody[ME-9F1] (E-AB-F1395D)