PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] (E-AB-F1192UD)
![PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD366/Tim-3 |
| Synonyms | TIMD3, HAVcr-2, TIM3, TIMD-3 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Inhibitory Molecules |
| Clone No. | RMT3-23 |
| Conjugation | PE |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
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