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100Tests $ 57.00
50Tests $ 32.00
100Tests×2 $ 100.00
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For research use only.

Background CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas<sup>lpr</sup> and MRL-Fas<sup>gld</sup> mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Alternate Names B220
Clone No
Host Rat
Reactivity Mouse
Isotype Rat IgM, κ
Isotype Control
Application
FCM
Cellular Localization
Membrane
Form Liquid
Conjugation
PE
Conjugation information PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

Elab Fluor®Red 780

Elab Fluor®Violet 450

FITC

PE

PE/Cyanine 5

PE/Cyanine 5.5

PE/Cyanine 7

PE/Elab Fluor®594

PerCP

PerCP/Cyanine 5.5

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