PE/Cyanine5 Anti-Rat CD172a(SIRPα) Antibody[OX-41] (AN00652G)

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Size	Price	Qty
100Tests	$ 70.00	- +
50Tests	$ 39.00	- +
100Tests×2	$ 126.00	- +

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Isotype	Mouse IgG2a, κ
Host	Mouse
Reactivity	Rat
Applications	FCM
Clonality	Monoclonal
Abbre	CD172a
Synonyms	SIRPa, PTPNS1, BIT, MFR, p84, CD172 antigen-like family member A,, AN00652
Swissprot	P97710
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Clone No.	OX-41
Conjugation	PE/Cyanine 5
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	Rat CD172a, also known as a signal-regulatory protein 伪 (SIRP伪), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.