PE/Cyanine7 Anti-Human CD11a Antibody[HI111] (E-AB-F1316H)
For research use only.
Conjugation: PE/Cyanine 7
APC Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 7 PerCP/Cyanine 5.5 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | CD11a |
| Synonyms | CD11 antigen-like family member A, CD11a, Integrin alpha-L, Itgal, LFA-1A, Ly-15, Lymphocyte antigen 15 |
| Swissprot | |
| Cellular Localization | Membrane |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroinflammation, Neuroscience |
| Clone No. | HI111 |
| Conjugation | PE/Cyanine 7 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
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