PE/Cyanine7 Anti-Human CD80 Antibody[2D10] (E-AB-F1232H)

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Cell Markers

Size	Price	Qty
100Tests	$ 240.00	- +
20Tests	$ 100.00	- +
100Tests×2	$ 360.00	- +

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Conjugation: PE/Cyanine 7

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Isotype Control	PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Abbre	CD80
Synonyms	B7BB1, B7-1, T-lymphocyte activation antigen CD80
Swissprot	P33681
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology, Innate Immunity
Clone No.	2D10
Conjugation	PE/Cyanine 7
Conjugation Information	PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.