PE/Cyanine7 Anti-Human/Monkey CD16 Antibody[3G8] (E-AB-F1236H)
![PE/Cyanine7 Anti-Human/Monkey CD16 Antibody[3G8] - 1](http://file.elabscience.com/assets/images/loading.png)
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For research use only.
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human, Rhesus, Cynomolgus |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21] |
| Abbre | CD16 |
| Synonyms | Fc gamma receptor, Fc gamma receptor 3, FcγRIII |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Clone No. | 3G8 |
| Conjugation | PE/Cyanine 7 |
| Conjugation Information | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
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