PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] (E-AB-F1235H)
![PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
| Alternate Names | ITGAV, Integrin alpha-V, Integrin αV chain, Vitronectin Receptor, αV integrin |
| Clone No | |
| Leadtime | Order now, ship in 3 days |
| Background | CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
| Abbre | CD51 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype | Rat IgG1, κ |
| Isotype Control | E-AB-F09822H |
| Applications |
FCM
|
| Research Areas | Angiogenesis;Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Stem Cells |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | PE/Cyanine 7 |
| Conjugation Information | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
Other Clones
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Other Formats
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APC
Biotin
None (AF/LE)
PE
PE/Cyanine 7
Unconjugated
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