PE/Elab Fluor®594 Anti-Human CD135 Antibody[BV10(BV10A4)] (AN00407P)
![PE/Elab Fluor<sup>®</sup>594 Anti-Human CD135 Antibody[BV10(BV10A4)] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: PE/Elab Fluor®594
Elab Fluor® Violet 450 Elab Fluor®488 Elab Fluor®647 FITC PE PE/Cyanine 5 PE/Elab Fluor®594 Unconjugated Show More
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | PE/Elab Fluor® 594 Mouse IgG1, κ Isotype Control[MOPC-21] |
| Abbre | CD135 |
| Synonyms | FMS-like tyrosine kinase-3, FLT-3, STK-1, Flk-2 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | BV10(BV10A4) |
| Conjugation | PE/Elab Fluor®594 |
| Conjugation Information | PE/Elab Fluor® 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | CD135 is a 130-160 kD type III tyrosine kinase receptor expressed on CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. CD135 is also expressed on malignant hematopoietic cells including AML, ALL and CML-BC. CD135, also known as FMS-like tyrosine kinase-3, FLT3, STK-1, and Flk-2, is a growth factor receptor that binds the FLT3 ligand to promote the growth and differentiation of primitive hematopoietic cells. The intracytoplasmic domain of CD135 is modified by phosphorylation and has been shown to interact with Grb2, SOCS1, VAV1, and Shc. |
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