PE/Elab Fluor® 594 Anti-Human/Mouse Integrin β7 Antibody[FIB21] (AN00423P)
![PE/Elab Fluor<sup>®</sup> 594 Anti-Human/Mouse Integrin β7 Antibody[FIB21] - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: PE/Elab Fluor®594
APC Elab Fluor®647 PE PE/Elab Fluor®594 PerCP/Cyanine 5.5 Show More
| Isotype | Rat IgG2b, κ |
| Host | Rat |
| Reactivity | Human, Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Abbre | Integrin β7 |
| Synonyms | β7 Integrin, integrin βp, ITGB7 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | FIB21 |
| Conjugation | PE/Elab Fluor®594 |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin. |
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