Pepsinogen C/PGC Monoclonal Antibody (AN200124P)

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	100μL	$ 380.00

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Verified Samples	Verified Samples in IHC: Human stomach
Dilution	IHC-P 1:50-1:200,
Isotype	IgG1
Host	Mouse
Reactivity	Human
Applications	IHC-P
Clonality	Monoclonal
Immunogen	Recombinant Human Pepsinogen C / PGC protein
Abbre	PGC
Synonyms	PGC, PEPC, PGII, gastricsin, Pepsinogen C, Pepsinogen II, PGC p
Swissprot	P20142
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Signal Transduction, Cancer, Microbiology, Metabolism
Clone No.	6F7
Conjugation	Unconjugated
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping	Ice bag
background	Pepsiongen II is a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself. Among endoscopy clinic patients, PGII is a sensitive marker for extension of nonatrophic gastritis toward the corpus. PGI is a stable biomarker in assessment of fundic atrophy and has similar accuracy to PGI/PGII ratio among populations with prevalent nonatrophic pangastritis. Research also showed that decreased PG I level and PG I/II ratio are risk factors for gastric cancer. Combined use of serum PG I level and PG I/II ratio may help the early diagnosis of gastric cancer.

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Unconjugated