PerCP/Cyanine5.5 Anti-Human CD28 Antibody[CD28.2] (E-AB-F1195J)

Name: PerCP/Cyanine5.5 Anti-Human CD28 Antibody[CD28.2]
Brand: Elabscience
SKU: E-AB-F1195J
Price: 120.0 USD
Availability: InStock

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PerCP/Cyanine5.5 Anti-Human CD28 Antibody[CD28.2] - 1

Size	Price	Qty
100Tests	$ 264.00	- +
20Tests	$ 120.00	- +
100Tests×2	$ 396.00	- +

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Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Abbre	CD28
Synonyms	GPSAT, GYPA, HGpMiX, MNS, PAS2
Swissprot	P10747
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Costimulatory Molecules, Immunology
Clone No.	CD28.2
Conjugation	PerCP/Cyanine 5.5
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.