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All Size Price Qty
100μg $ 220.00
25μg $ 90.00
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For research use only.

Alternate Names Siglec2,  B-cell receptor CD22,  B-lymphocyte cell adhesion molecule,  BL-CAM,  CD22,  Cd22,  Lyb-8,  Sialic acid-binding Ig-like lectin 2,  Siglec-2,  T-cell surface antigen Leu-14
Clone No
Leadtime Order now, ship in 3 days
Background The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig µ chain are augmented in the presence of Cy34.1 mAb.
Abbre CD22
Swissprot
Host Mouse
Reactivity Mouse
Clonality Monoclonal
Isotype Mouse IgG1, κ
Isotype Control E-AB-F09793J
Applications
FCM
Research Areas Immunology
Cellular Localization
Membrane
Form Liquid
Concentration
0.2 mg/mL
Conjugation PerCP/Cyanine 5.5
Conjugation Information PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date 12 months
Shipping Ice bag
Cat.No. Product Name Sizes
E-CK-A105 10×ACK Lysis Buffer 500mL , 200mL , 100mL
E-CK-A107 Cell Staining Buffer 500mL , 200mL , 100mL
Other Clones

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Other Formats

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APC

Biotin

Elab Fluor®488

Elab Fluor®647

Elab Fluor®700

Elab Fluor®Violet 450

FITC

None (AF/LE)

PE

PE/Cyanine 5

PE/Cyanine 5.5

PE/Cyanine 7

PerCP/Cyanine 5.5

Unconjugated

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