PFKM Polyclonal Antibody (E-AB-52666)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer |
| Dilution | IHC 1:40-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PFKM |
| Abbre | PFKM |
| Synonyms | 6 Phosphofructokinase Muscle Type, 6-phosphofructokinase, 6-phosphofructokinase muscle type, EC 2.7.1.1, EC 2.7.1.11, GSD7, K6PF, MGC8699, PFK, PFK-A, PFKA, PFKL, PFKM, PFKP, PFKX, Phosphofructo 1 Kinase Isozyme A, Phosphofructo-1-kinase isozyme A, muscle type |
| Swissprot | |
| Cellular Localization | Cytosol, 6-phosphofructokinase complex, cytosol, Extracellular region or secreted, extracellular exosome, Nucleus, Plasma Membrane, apical plasma membrane, Other locations: sperm principal piece. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. |
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