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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human PFKP
Abbre PFKP
Synonyms 1200015H23Rik,  6 phosphofructokinase,  6 phosphofructokinase type C,  6-phosphofructokinase,  6-phosphofructokinase type C,  9330125N24Rik,  FLJ40226,  K6PP,  MGC105718,  PFK,  PFK C,  PFK-C,  PFKF,  PFKP,  Phospho,  Phosphofructo 1 kinase isozyme C,  fibroblast type,  platelet type
Swissprot
Cellular Localization Cytosol, Extracellular region or secreted, extracellular exosome, extracellular matrix, Nucleus, Other locations: cytoplasm, membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.
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Unconjugated

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