PFN2 Polyclonal Antibody (E-AB-12624)

For research use only.
Verified Samples |
Verified Samples in WB: Human brain Verified Samples in IHC: Human brain, Human liver cancer |
Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PFN2 |
Abbre | PFN2 |
Synonyms | D3S1319E, PFL, PFN 2, PROF2, Pfn2, Profilin II, Profilin-2, Profilin2, ProfilinII |
Swissprot | |
Calculated MW | 15 kDa |
Cellular Localization | Cytoplasm>cytoskeleton. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. |
Other Clones
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Other Formats
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Unconjugated
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