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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human PIM1
Abbre PIM1
Synonyms Oncogene PIM 1,  Oncogene PIM1,  PIM,  PIM 1,  PIM1,  PIM3,  Pim 1 kinase,  Pim 1 oncogene,  Pim2,  Proto oncogene serine/threonine protein kinase Pim 1,  Proto-oncogene ,  pim 1 kinase 44 kDa isoform,  pim 1 oncogene (proviral integration site 1),  pim1 kinase 44 kDa isoform
Swissprot
Cellular Localization Cytoplasm. Nucleus and Cell membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Signal Transduction,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.
Other Clones

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Unconjugated

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