PIM1 Polyclonal Antibody (E-AB-14694)
For research use only.
Verified Samples |
Verified Samples in IHC: Human thyroid cancer |
Dilution | IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PIM1 |
Abbre | PIM1 |
Synonyms | Oncogene PIM 1, Oncogene PIM1, PIM, PIM 1, PIM1, PIM3, Pim 1 kinase, Pim 1 oncogene, Pim2, Proto oncogene serine/threonine protein kinase Pim 1, Proto-oncogene , pim 1 kinase 44 kDa isoform, pim 1 oncogene (proviral integration site 1), pim1 kinase 44 kDa isoform |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus and Cell membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. |
Other Clones
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Other Formats
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Unconjugated
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