PKC delta Polyclonal Antibody (E-AB-14675)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain Verified Samples in IHC: Human liver cancer, Human thyroid cancer |
| Dilution | WB 1:200-1:1000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PRKCD |
| Synonyms | CVID9, D14Ertd420e, KPCD, Kinase PKC delta, MAY 1, MAY1, MGC49908, PCKd, PKC d, PKC delta, PKCD, PKCdelta, PRKC D, PRKC delta, Prkcd, Protein Kinase C delta, Protein Kinase Cdelta, Protein kinase C delta VIII, Protein kinase C delta type, Tyrosine, nPKC delta, nPKC-delta |
| Swissprot | |
| Calculated MW | 78 kDa |
| Cellular Localization | Cytoplasm. Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. |
Other Clones
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Unconjugated
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