PLAUR Polyclonal Antibody (E-AB-14303)
For research use only.
| Verified Samples |
Verified Samples in WB: A549 Verified Samples in IHC: Human lung cancer, Human colon cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PLAUR |
| Abbre | PLAUR |
| Synonyms | CD 87, CD87, CD87 antigen, MO 3, MO3, Monocyte activation antigen Mo3, PLAUR, Plasminogen activator receptor urokinase, Plasminogen activator urokinase receptor, U PAR, U-PAR, UPA receptor, u plasminogen activator receptor, u-plasminogen activator receptor form 2, uPAR |
| Swissprot | |
| Calculated MW | 37 kDa |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Other Clones
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Unconjugated
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