PLK4 Polyclonal Antibody (E-AB-18272)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human breast cancer |
| Dilution | IHC 1:35-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PLK4 |
| Abbre | PLK4 |
| Synonyms | PLK 4, PLK-4, PLK4, Polo like Kinase 4, Polo-like kinase 4, Protein serine/threonine kinase, SAK, Serine/Threonine Kinase 18, Serine/threonine kinase, Serine/threonine protein kinase 18, Serine/threonine protein kinase PLK4, Serine/threonine protein kinase Sak |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome>centriole. Nucleus>nucleolus. Cleavage furrow. Associates with centrioles throughout the cell cycle. According to PubMed:16244668, it is not present at cleavage furrows. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. |
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