Podoplanin Monoclonal Antibody (ELAB6972-M)
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For research use only.
| Isotype | Mouse IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-P |
| Abbre | Podoplanin |
| Synonyms | Podoplanin |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | Tonsil |
| Concentration | 1 mg/mL |
| Clone | YN02516m |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
| background | Podoplanin, also known as D2-40 or M2A, is a 38 kDa type I transmembrane mucin with multiple O-glycosylation sites. It is highly expressed in lymphatic endothelial cells, but not in blood vessels. In addition, it is also expressed in a variety of cells, such as mesothelial cells and type I alveolar epithelial cells,follicular dendritic cells, reticular cells, ovarian and testicular germ cells. Podoplanin is a very useful marker to distinguish malignant mesothelioma and adenocarcinoma, seminoma and follicular dendritic cell sarcoma. It is also the main choice to show and quantify lymphatic and intravascular tumor infiltration. |
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