Porcine EGFR Antibody Pair Set (E-KAB-0672)
For research use only.
| Background |
EGFR;also named as ERBB1;is a cell-surface receptor for members of the epidermal growth factor family ( EGF-family ) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12;encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression;including cell proliferation;apoptosis;angiogenesis;and metastatic spread. Mutations in this gene are associated with lung cancer.
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| Synonyms |
ErbB-1, ErbB1, ERBB, HER1, mENA
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| Swissprot | |
| Reactivity |
Porcine
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| Specificity |
Detects Porcine EGFR in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
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| Expiration date |
12 months
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