Porcine TFPI Antibody Pair Set (E-KAB-0674)
For research use only.
| Background |
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor ( TF ) -dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex , which proteolytically activates additional proteases ( factors IX and X ) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity , specificity and cellular localization.
|
| Synonyms |
EPI, LACI, TFI, TFPI1, lipoprotein-associated coagulation inhibitor
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| Swissprot | |
| Reactivity |
Porcine
|
| Specificity |
Detects Porcine TFPI in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
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Other Clones
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