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For research use only.

Verified Samples Verified Samples in WB: K562, Human fetal liver
Verified Samples in IHC: Human thyroid cancer, Human colon cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PPM1F
Abbre PPM1F
Synonyms CAMKP,  Ca(2+)/calmodulin-dependent protein kinase phosphatase,  CaM-kinase phosphatase,  CaMKPase,  FEM 2,  KIAA0015,  POPX2,  PP2C phosphatase,  PPM1F,  Partner of PIX 2,  Ppm1f,  Protein fem-2 homolog,  Protein phosphatas,  Protein phosphatase 1F (PP2C domain containing),  hFEM-2
Swissprot
Calculated MW 50 kDa
Cellular Localization Cytosol, Other locations: perinuclear region of cytoplasm, protein complex.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell biology,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases.PP2C family members are known to be negative regulators of cell stress response pathways.This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases.Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase.
Other Clones

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Unconjugated

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