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For research use only.

Verified Samples Verified Samples in WB: K562, 293T
Verified Samples in IHC: Human thyroid cancer, Human breast cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PPOX
Abbre PPOX
Synonyms MGC8485,  PPO,  PPOX,  Protoporphyrinogen oxidase,  V290M,  VP,  Variegate porphyria
Swissprot
Calculated MW 51 kDa
Cellular Localization Mitochondrion inner membrane.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Tags and Cell markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX.Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane.Alternatively spliced transcript variants encoding the same protein have been identified.
Other Clones

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Unconjugated

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