PPP1CB Polyclonal Antibody (E-AB-10548)
For research use only.
Verified Samples |
Verified Samples in WB: Hela Verified Samples in IHC: Human tonsil, Human cervical cancer |
Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PPP1CB |
Abbre | PPP1CB |
Synonyms | MGC3672, PP 1B, PP-1B, PP1B, PP1beta, PPP1CB, PPP1CD, Protein phosphatase 1, Protein phosphatase 1 beta, Protein phosphatase 1 catalytic subunit beta isoform, Protein phosphatase 1 delta, beta isozyme, catalytic subunit, de |
Swissprot | |
Calculated MW | 37 kDa |
Cellular Localization | Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus. Highly mobile in cells and can be relocalized through interaction with targeting subunits. In the presence of PPP1R8 relocalizes from the nucleus to nuclear speckles. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Other Clones
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Other Formats
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Unconjugated
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