PPP1R13L Polyclonal Antibody (E-AB-15724)

For research use only.
Verified Samples |
Verified Samples in WB: MCF-7, Hela Verified Samples in IHC: Human colon cancer, Human liver cancer |
Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PPP1R13L |
Abbre | PPP1R13L |
Synonyms | IASPP, Inhibitor of ASPP protein, NFkB interacting protein 1, NKIP1, PPP1R13B-like protein, PPP1R13L, Protein iASPP, RAI, RelA-associated inhibitor, inhibitor of apoptosis stimulating protein of p53, protein phosphatase 1 regulatory (inhibitor) subunit 13 like |
Swissprot | |
Calculated MW | 89 kDa |
Cellular Localization | Nuclear |
Concentration | 0.6 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73. |
Other Clones
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Other Formats
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Unconjugated
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