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For research use only.

Verified Samples Verified Samples in WB: MCF-7, Hela
Verified Samples in IHC: Human colon cancer, Human liver cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PPP1R13L
Abbre PPP1R13L
Synonyms IASPP,  Inhibitor of ASPP protein,  NFkB interacting protein 1,  NKIP1,  PPP1R13B-like protein,  PPP1R13L,  Protein iASPP,  RAI,  RelA-associated inhibitor,  inhibitor of apoptosis stimulating protein of p53,  protein phosphatase 1 regulatory (inhibitor) subunit 13 like
Swissprot
Calculated MW 89 kDa
Cellular Localization Nuclear
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
Other Clones

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Unconjugated

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