PPP1R15A Polyclonal Antibody (E-AB-19394)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human lung cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PPP1R15A |
| Abbre | PPP1R15A |
| Synonyms | Apoptosis associated protein, GADD 34, Growth arrest and DNA damage inducible 34, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PR15A, Ppp1r15a, Protein phosphatase 1 regulatory (inhibitor |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum. |
| Concentration | 1.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | PPP1R15A (Protein Phosphatase 1 Regulatory Subunit 15A) is a Protein Coding gene. Diseases associated with PPP1R15A include Malignant Pleural Mesothelioma. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Activation of cAMP-Dependent PKA. GO annotations related to this gene include protein kinase binding.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. |
Other Clones
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Unconjugated
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