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For research use only.

Verified Samples Verified Samples in IHC: Human tonsil, Human esophagus cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human PPP1R3C
Abbre PPP1R3C
Synonyms regulatory (inhibitor) subunit 3C,   regulatory inhibitor subunit 5,  OTTHUMP00000020089,  PP1 subunit R5,  PPP1R5 ,  PPR3C,  Phosphatase 1,  Protein phosphatase 1 regulatory subunit 3C,  Protein phosphatase 1 regulatory subunit 5,  Protein t,  ppp1r3c,  protein phosphatase 1
Swissprot
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Metabolism,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
Other Clones

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Unconjugated

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