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For research use only.

Verified Samples Verified Samples in IF: U2OS
Dilution IF 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human PPP2R4
Abbre PPP2R4
Synonyms PP2A,  PPP2R4,  PR53,  PTPA
Swissprot
Calculated MW 31 kDa/33 kDa/36 kDa/40 kDa
Cellular Localization Cytoplasm, Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Unconjugated

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