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For research use only.

Verified Samples Verified Samples in WB: Human colon
Verified Samples in IHC: Human breast cancer, Human lung cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human PRKAR1B
Abbre PRKAR1B
Synonyms KAP1,  PKARI beta,  PRKAR 1,  PRKAR 1B,  PRKAR1,  PRKAR1B protein,  Prkar1b,  Protein kinase cAMP dependent regulatory type I beta,  RIbeta,  cAMP dependent protein kinase type I beta regulatory subunit,  cAMP-dependent protein kinase type I-beta regulatory subunit
Swissprot
Calculated MW 43 kDa
Cellular Localization Cytosol, Plasma Membrane, Other locations: cAMP-dependent protein kinase complex, ciliary base.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.
Other Clones

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Unconjugated

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