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For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse lung, Mouse kidney Verified Samples in IF: C6, HeLa, NIH/3T3 |
| Dilution | IHC 1:50-1:100, IF 1:50-1:100 |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human PRKCB (NP_002729.2). |
| Synonyms | PKC-beta, PKCB, PRKCB, PRKCB1, PRKCB2 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Membrane. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Other Clones
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Unconjugated
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