PRMT7 Polyclonal Antibody (E-AB-10554)

For research use only.
Verified Samples |
Verified Samples in WB: Human liver |
Dilution | WB 1:500-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PRMT7 |
Abbre | PRMT7 |
Synonyms | ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine N-, Protein arginine methyltransferase 7, [Myelin basic protein]-arginine N-methyltransferase PRMT7 |
Swissprot | |
Calculated MW | 78 kDa |
Cellular Localization | Cytoplasm, cytosol. Nucleus. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene.Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor.Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing.May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers.Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT). |
Other Clones
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Other Formats
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Unconjugated
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