PSMD7 Polyclonal Antibody (E-AB-60920)
For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse spleen Verified Samples in IF: MCF-7 |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human PSMD7 (NP_002802.2). |
| Abbre | PSMD7 |
| Synonyms | MOV34, P40, PSMD7, Rpn8, S12 |
| Swissprot | |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome, extracellular region, Nucleus, nucleoplasm, nucleus, Other locations: ficolin-1-rich granule lumen, membrane, proteasome complex, proteasome regulatory particle, secretory granule lumen. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. |
Other Clones
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Other Formats
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Unconjugated
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