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200μL $ 530.00
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For research use only.

Verified Samples Verified Samples in IHC: Mouse spleen
Verified Samples in IF: MCF-7
Dilution IHC 1:50-1:200,  IF 1:50-1:200
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC,  IF
Clonality Polyclonal
Immunogen Recombinant fusion protein of human PSMD7 (NP_002802.2)
Abbre PSMD7
Synonyms MOV34,  P40,  PSMD7,  Rpn8,  S12,  S12抗体
Swissprot
Calculated MW 37 kDa
Cellular Localization Cytosol, Extracellular region or secreted, Extracellular exosome, Extracellular region, Nucleus, Nucleoplasm, Membrane, Proteasome complex, Proteasome regulatory particle, Secretory granule lumen
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
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