PSMD9 Polyclonal Antibody (E-AB-10569)
For research use only.
Verified Samples |
Verified Samples in WB: A549, Human liver cancer, Human fetal kidney Verified Samples in IHC: Human ovarian cancer |
Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human PSMD9 |
Abbre | PSMD9 |
Synonyms | 26S proteasome non ATPase regulatory subunit 9, 26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, Homolog of rat Bridge 1, MGC8644, Proteasome (prosome macropain) 26S subunit non ATPase 9, Proteasome 26S non ATPase regul, p27 |
Swissprot | |
Calculated MW | 25 kDa |
Cellular Localization | Cytosol, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm, proteasome regulatory particle. |
Concentration | 0.3 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. |
Other Clones
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Unconjugated
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