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For research use only.

Verified Samples Verified Samples in WB: A549, Human liver cancer, Human fetal kidney
Verified Samples in IHC: Human ovarian cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human PSMD9
Abbre PSMD9
Synonyms 26S proteasome non ATPase regulatory subunit 9,  26S proteasome non-ATPase regulatory subunit 9,  26S proteasome regulatory subunit p27,  Homolog of rat Bridge 1,  MGC8644,  Proteasome (prosome macropain) 26S subunit non ATPase 9,  Proteasome 26S non ATPase regul,  p27
Swissprot
Calculated MW 25 kDa
Cellular Localization Cytosol, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm, proteasome regulatory particle.
Concentration 0.3 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene.
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Unconjugated

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