PTN Polyclonal Antibody (E-AB-12851)
For research use only.
| Verified Samples |
Verified Samples in WB: Human colon |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PTN |
| Abbre | PTN |
| Synonyms | HARP, HB-GAM, HBBM, HBGAM, HBGF-8, HBGF8, HBNF, HBNF-1, HBNF1, Heparin binding growth associated molecule, Heparin binding growth factor 8, Heparin binding neurite outgrowth promoting factor 1, Heparin-bi, Heparin-binding brain mitogen, heparin affin regulatory protein |
| Swissprot | |
| Calculated MW | 19 kDa |
| Cellular Localization | Secreted. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Pleiotrophin (PTN) also known as heparin-binding brain mitogen (HBBM) or heparin-binding growth factor 8 (HBGF-8) or neurite growth-promoting factor 1 (NEGF1) or heparin affinity regulatory peptide (HARP) or heparin binding growth associated molecule (HB-GAM) is a protein that in humans is encoded by the PTNgene.Pleiotrophin is an 18-kDa growth factor that has a high affinity for heparin.It is structurally related to midkine and retinoic acid induced heparin-binding protein.Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells.Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. |
Other Clones
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Other Formats
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Unconjugated
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