PTPA Polyclonal Antibody (E-AB-53148)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human ovarian cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PTPA |
| Abbre | PTPA |
| Synonyms | regulatory subunit B-prime, KIAA0044 , MGC2184 , PP2A, PP2A phosphatase activator , PP2A subunit B', PP2A subunit B' PR53 isoform , PP2A subunit B' isoform PR53, PPP2R4, PR53 , PR53 isoform, Phosphotyrosyl phosphatase activator, Pro, Protein phosphatase 2, subunit B'' |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Other Clones
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Other Formats
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Unconjugated
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