Purified Anti-Human CD158b Antibody[DA013] (AN015430P)
| Alternate Names | NKAT, CD158B, KIR2DL, CD158B1, NKAT6, KIR2DL2, p58.2 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. KIRs with long cytoplasmic domains contain ITIM motifs and possess inhibitory functions, while those with short cytoplasmic tails lack ITIMs and have activating functions. Fifteen polymorphic KIR genes have been reported in humans.CD158b1, CD158b2, and CD158j are 33-38 kD glycoproteins with two extracellular Ig-like domains and either a long cytoplasmic tail with ITIM motifs (KIR2DL2/KIR2DL3) or a short tail containing an ITAM-associated activating motif (KIR2DS2). |
| Immunogen | Recombinant Human CD158b protein |
| Abbre | CD158b |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | Purified Mouse IgG2b, κ Isotype Control[MPC-11], Functional Grade |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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