Purified Anti-Human CD177 Antibody[MEM-166] (AN014790P)
| Alternate Names | UNQ, PRO, Polycythemia Rubra Vera Protein, PRV, CD177, HNA-2a, HNA2A, NB1, NB1 GP, PRV-1, PRV1, NB1GP, CD177 Antigen, Human Neutrophil Alloantigen 2a, NB1 Glycoprotein, Polycythemia Rubra Vera Protein 1, UNQ595, PRO1181, HNA-2a |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood Granulocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD177 is also known as neutrophil specific antigen 1, NB1, and polycythemia rubra vera 1. It is a member of the uPAR family and is a GPI-linked cell surface glycoprotein with a molecular weight of 60 kD. CD177 is expressed on granulocytes and bone marrow progenitors (early erythroblasts, megakaryocytes). It is thought to be involved in allogeneic and autoimmune responses to neutrophils. |
| Immunogen | Recombinant Human CD177 protein |
| Abbre | CD177 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Applications |
FCM
|
| Research Areas | CDs;Immunology |
| Cellular Localization |
Membrane, Secreted
|
| Tissue Specificity |
Highly expressed in normal bone marrow and weakly expressed in fetal liver
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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