Purified Anti-Human CD184 Antibody[12G5], Functional Grade (E-AB-F11570)
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For research use only.
| Alternate Names | LCR, CXCR, C-X-C chemokine receptor type, LAP, CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, CXCR4, C-X-C chemokine receptor type 4, Fusin, SDF 1 receptor, Fusin, LESTR, CD184 antigen, Chemokine (C X C motif) receptor 4, Chemokine CXC Motif Receptor 4, C-X-C motif chemokine receptor 4, CXCR-4, CXC-R4, LAP 3, Leukocyte derived seven transmembrane domain receptor, Leukocyte-derived seven transmembrane domain receptor, Lipopolysaccharide associated protein 3, Neuropeptide Y receptor Y3, NPYY3, Probable G protein coupled receptor lcr1 homolog, SDF-1 receptor, SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR, Stromal cell derived factor 1 receptor, Stromal cell-derived factor 1 receptor |
| Clone | |
| Leadtime | Inquire |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes cell |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells);Block Reported in the literaturee |
| Background | This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Immunogen | Recombinant Human CD184 protein |
| Abbre | CD184 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4], Functional Grade |
| Applications |
FCM;Block
|
| Research Areas | Immunology;Microbiology;Neuroscience;Stem Cells;Cancer;Metabolism |
| Concentration |
≥ 1 mg/mL
|
| Conjugation | None (AF/LE) |
| Storage Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
| Application References | Berndt C, et al. Proc Natl Acad Sci USA. 1996 Oct;95(21):12556. |
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