Purified Anti-Human CD19 Antibody[4G7], Functional Grade (E-AB-F11270)
![Purified Anti-Human CD19 Antibody[4G7], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
Elab Fluor®700 Elab Fluor®Violet 450 None (AF/LE) PE/Cyanine 7 PE/Elab Fluor®594 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), FA Reported in the literature |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM, FA |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD19 protein |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Abbre | CD19 |
| Synonyms | CVID, B-lymphocyteantigenCD, B-lymphocyte antigen CD, T-cellsurfaceantigenLeu, Differentiation antigen CD, T-cell surface antigen Leu, B-lymphocytesurfaceantigenB, B-lymphocyte surface antigen B, B4, CVID3, CD19, B-lymphocyteantigenCD19, B-lymphocytesurfaceantigenB4, T-cellsurfaceantigenLeu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, B4, CVID3, CD19, CD19 molecule |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology, Stem Cells |
| Clone | 4G7 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN008610 | Purified Anti-Human CD19 Antibody[HIB19], Functional Grade | HIB19 |
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