Purified Anti-Human CD269 Antibody[19F2] (AN009510P)
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For research use only.
| Alternate Names | TNR, Tumor necrosis factor receptor superfamily member, TNFRSF, TNFRSF17, BCM, BCMA, CD269, TNFRSF13A, B cell maturation antigen, B cell maturation factor, B cell maturation protein, B-cell maturation protein, CD269 antigen, TNR17, Tumor necrosis factor receptor superfamily member 17, TNFRSF17 |
| Clone | |
| Verified Samples | Verified Samples in FCM: U266 cells |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD269, also known as B cell maturation antigen (BCMA), is a 27 kD, single pass transmembrane protein with one TNFR-Cys repeat on its extracellular domain. CD269 is a B cell maturation factor, essential for the long-term survival of plasma cells. It is expressed by plasmablasts, plasma cells, and germinal center B cells. The ligands of CD269 are BAFF and APRIL, and its cytoplasmic domain binds several of the TRAF family members. |
| Immunogen | Recombinant Human CD269 protein |
| Abbre | CD269 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | Purified Mouse IgG2a, κ Isotype Control[C1.18.4], Functional Grade |
| Applications |
FCM
|
| Research Areas | Cancer;Immunology;Signal Transduction;CDs;NF-kB Signaling Pathway |
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Expressed in mature B-cells, but not in T-cells or monocytes.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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