Purified Anti-Human CD277 Antibody[ICT01] (AN008880P)
![Purified Anti-Human CD277 Antibody[ICT01] - 1](http://file.elabscience.com/assets/images/loading.png)
| Alternate Names | BTF, BTN, Butyrophilin subfamily 3 member A, BTN3A, BTN3A1, BT3.1, BTF5, BTN3.1, CD277, Butyrophilin subfamily 3 member A1, BTN3A1 |
| Clone | |
| Verified Samples | Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding human CD277 gene |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | Butyrophilin subfamily 3A (BTN3A), also known as CD277, is a 56 kD type 1 transmembrane glycoprotein. The butyrophilin (BT)/B7 3A family includes three members, BTN3A1, BTN3A2, and BTN3A3, which share a highly conserved extracellular IgV-like domain. BTN3A is broadly expressed in various immune cells including T cells, B cells, NK cells, monocytes, dendritic cells, endothelial cells, and some tumor cells. It plays a role in T cell activation, regulating their proliferation and release of IFNƳ and other cytokines. |
| Immunogen | Recombinant Human CD277 protein |
| Abbre | CD277 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Human IgG1, κ |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Detected on T-cells, natural killer cells, dendritic cells and macrophages (at protein level). Ubiquitous. Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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