Purified Anti-Human CD294 Antibody[BM16] (AN011310P)
| Alternate Names | CD294, CD294 antigen, Chemoattractant receptor homologous molecule expressed on Th2 cells, chemoattractant receptor-homologous, Chemoattractant receptor-homologous molecule expressed on Th2 cells, CRTH 2, DP2 prostaglandin receptor, G Protein Coupled Receptor 44, GPR 44, Putative G protein coupled receptor 44, Putative G-protein coupled receptor 44, GPR, CRTH, PTGDR, CRTH2, DL1R, GPR44, PTGDR2, DP2, GPR44 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung. |
| Immunogen | Recombinant Human CD294 protein |
| Abbre | CD294 |
| Swissprot | |
| Host | Rat |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Applications |
FCM
|
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Widespread expression. High expression in stomach, small intestine, heart and thymus.
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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