Purified Anti-Human CD352 Antibody[W19035D] (AN003210P)
For research use only.
Conjugation: Unconjugated
APC Elab Fluor®488 Elab Fluor®647 FITC PE Unconjugated Show More
| Alternate Names | UNQ, SLAM Family Member, SLAMF, SLAMF6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000, Activating NK Receptor, NK-T-B-Antigen, SLAM Family Member 6, UNQ6123, PRO20080, NTB-A, KAL1, Ly108 |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM ≤ 0.2 µg per million cells in 100 µL volume |
| Background | NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases. |
| Immunogen | Recombinant Human CD352 protein |
| Abbre | CD352 |
| Swissprot | |
| Host | Rat |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3], Functional Grade |
| Applications |
FCM
|
| Research Areas | CDs;Immunology |
| Cellular Localization |
Cell membrane
|
| Tissue Specificity |
Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes
|
| Concentration |
≥1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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