Purified Anti-Human CD4 Antibody[RPA-T4], Functional Grade (E-AB-F11090)
For research use only.
Conjugation: None (AF/LE)
APC Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Red 780 Elab Fluor®Violet 450 Elab Fluor®Violet 500 Elab Fluor®Violet 540 Elab Fluor®Violet 610 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 PerCP PerCP/Cyanine 5.5 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Activ Activ - Reported in the literature, Block Block - Reported in the literature |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM, Activ, Block |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD4 protein |
| Abbre | CD4 |
| Synonyms | CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology |
| Clone | RPA-T4 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| E-AB-F12310 | Purified Anti-Human CD4 Antibody[OKT-4], Functional Grade | OKT-4 |
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