Purified Anti-Human CD45RO Antibody[UCHL1] (E-AB-F1139A)

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Cell Markers

Size	Price	Qty
100μg	$ 50.00	- +
25μg	$ 20.00	- +
100mg	$ 13800.00	- +
50mg	$ 9650.00	- +
25mg	$ 5500.00	- +
5mg	$ 1390.00	- +
1mg	$ 335.00	- +

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Conjugation: Unconjugated

Verified Samples	Verified Samples in FCM: Human peripheral blood lymphocytes
Dilution	FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)
Isotype	Mouse IgG2a, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Immunogen	Recombinant Human CD45RO protein
Abbre	CD45RO
Concentration	≥ 1 mg/mL
Buffer	Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Purification Method	>98%, Protein A/G purified
Research Areas	Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers, Stem Cells
Clone No.	UCHL1
Conjugation	Unconjugated
Storage	Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Shipping	Ice bag
background	CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.