Purified Anti-Human CD58 Antibody[TS2/9.1], Functional Grade (E-AB-F10680)
![Purified Anti-Human CD58 Antibody[TS2/9.1], Functional Grade - 1](http://file.elabscience.com/assets/images/loading.png)
For research use only.
Conjugation: None (AF/LE)
APC Biotin Elab Fluor®488 None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 7 PE/Elab Fluor®594 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Human peripheral blood lymphocytes |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells), Block Reported in the literature |
| Isotype | Mouse IgG1, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM, Block |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD58 protein |
| Isotype Control | Purified Mouse IgG1, κ Isotype Control[MOPC-21], Functional Grade |
| Abbre | CD58 |
| Synonyms | LFA, Ag3, CD58 antigen, Lymphocyte function-associated antigen 3, Surface glycoprotein LFA-3, LFA3, CD58, LFA-3 |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology |
| Clone | TS2/9.1 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells. |
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